RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-223
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
immunohistochemistry; RT-PCR;
Target
TWIST1;TGFBR2
Pathway
NA
PubMed ID
Title
Effect and mechanism of miR-223 on fibrosis-related signaling pathway in rat cardiomyocytes
Year
2020
Function
miR-223 may inhibit the activation of fibrosis-related signaling pathway in cardiomyocytes by down-regulating the expression of twist1 and TGF-betaR2 genes.